Biochemistry Paper Checker

Validate biochemistry manuscripts for IUPAC/IUBMB nomenclature, data deposition, experimental reproducibility, and leading biochemistry journal requirements.

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Biochemistry publishing requirements

Biochemistry manuscripts must follow IUPAC and IUBMB nomenclature for enzymes, proteins, and chemical compounds. Structural data must be deposited in the Protein Data Bank (PDB); nucleotide sequences in GenBank or EMBL-EBI. Top biochemistry journals (Journal of Biological Chemistry, Biochemistry, FEBS Journal) require complete materials and methods sections with sufficient detail for reproducibility, including commercial sources for reagents, instrument specifications, and software versions. Our checker validates biochemistry-specific requirements.

Biochemistry-specific checks

Enzyme nomenclature

Check that enzymes are named following IUBMB recommendations with EC numbers where appropriate.

Data deposition

Verify accession numbers are provided for deposited sequences or structures.

Reagent sources

Flag missing commercial source information for antibodies and key reagents.

Reproducibility details

Check that methods include sufficient detail for experiment replication.

Statistical reporting

Validate n values, statistical tests, and error bar descriptions in figures.

Supplementary data

Confirm supplementary files are referenced and described in the manuscript.

Checks relevant to this topic

Part of our 80+ automated checks

IUPAC nomenclature

Chemical and enzyme names follow IUPAC/IUBMB conventions.

Accession numbers

Database accession numbers for deposited data.

Materials sourcing

Commercial sources for antibodies and critical reagents.

Statistical methods

n values, error measures, and statistical tests specified.

The practical edge your peers already use

Across disciplines and career stages, researchers reduce bottlenecks and submit with confidence: clearer drafts, easier guideline compliance, and less back and forth with co‑authors and reviewers.

I use it to review my students' papers. It instantly highlights typos, missing references, and unclear sections, helping me focus my feedback on the quality of the research instead of surface errors.

Ilyass, Professor in Mechanical Engineering, ÉTS Montréal

Ilyass

Professor in Mechanical Engineering, ÉTS Montréal

I relied on it throughout my thesis to strengthen my writing. It suggested clearer phrasing, improved flow between sections, and ensured my references were complete before the final deadline.

Manon, Master's Student in Speech Therapy

Manon

Master's Student in Speech Therapy

I write research in both Portuguese and English, and it adapts perfectly to either language. It provided precise feedback in Portuguese, helping me maintain academic tone and consistency across my drafts.

Afonso, PhD Candidate, UFPE

Afonso

PhD Candidate, UFPE

It gave excellent advice on how to rephrase and present ideas more clearly and concisely. The suggestions helped me refine my arguments and make my research more impactful.

Félix, Postdoc Researcher, Max Planck Institute for Evolutionary Biology

Félix

Postdoc Researcher, Max Planck Institute for Evolutionary Biology

A round of suggestions helped to generally refine the text of my paper and, moreover, to present some of its key points in a more focused form.

Oleg, Professor, Pirogov Russian National Research Medical University

Oleg

Professor, Pirogov Russian National Research Medical University

I use it to review my students' papers. It instantly highlights typos, missing references, and unclear sections, helping me focus my feedback on the quality of the research instead of surface errors.

Ilyass, Professor in Mechanical Engineering, ÉTS Montréal

Ilyass

Professor in Mechanical Engineering, ÉTS Montréal

I relied on it throughout my thesis to strengthen my writing. It suggested clearer phrasing, improved flow between sections, and ensured my references were complete before the final deadline.

Manon, Master's Student in Speech Therapy

Manon

Master's Student in Speech Therapy

I write research in both Portuguese and English, and it adapts perfectly to either language. It provided precise feedback in Portuguese, helping me maintain academic tone and consistency across my drafts.

Afonso, PhD Candidate, UFPE

Afonso

PhD Candidate, UFPE

It gave excellent advice on how to rephrase and present ideas more clearly and concisely. The suggestions helped me refine my arguments and make my research more impactful.

Félix, Postdoc Researcher, Max Planck Institute for Evolutionary Biology

Félix

Postdoc Researcher, Max Planck Institute for Evolutionary Biology

A round of suggestions helped to generally refine the text of my paper and, moreover, to present some of its key points in a more focused form.

Oleg, Professor, Pirogov Russian National Research Medical University

Oleg

Professor, Pirogov Russian National Research Medical University

Frequently asked questions

Protein structures: Protein Data Bank (PDB). Nucleotide sequences: GenBank, EMBL, DDBJ. Proteomics data: ProteomeXchange. Mass spectrometry: PRIDE database. Most journals require deposition before acceptance and accession numbers in the manuscript.

Biochemistry journals expect full reproducibility: list all reagents with commercial source and catalog number, specify instrument models and software versions, describe all steps in sufficient detail that another lab could replicate the experiment.