Nature Medicine Submission Requirements
Validate your translational or clinical manuscript against Nature Medicine's requirements, a Nature-portfolio journal for biomedical and clinical research.
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What Nature Medicine requires
Nature Medicine is a Nature-portfolio journal publishing biomedical, translational, and clinical research. It applies the shared Nature-portfolio policies, a mandatory data availability statement with specific repositories, a life-sciences reporting summary, CRediT author contributions, competing-interests declarations, and code availability where relevant, combined with clinical-research expectations such as prospective trial registration and CONSORT reporting for trials. CheckMyManuscript flags the presence and structure of these elements before submission.
Nature Medicine requirements, and what CMM checks
Nature-portfolio policies apply (see the Nature checker), plus clinical-research items for trials.
Data availability statement
✓ CMM checks thisMandatory, naming repositories and accession numbers (e.g. GEO/SRA/ENA for sequencing, PDB for structures).
Flag: 'data available on request' with no justification.
Source: nature.com · verified Jun 16, 2026
Reporting summary
✓ CMM checks thisA completed life-sciences reporting summary submitted with the manuscript.
Source: nature.com · verified Jun 16, 2026
CRediT & competing interests
✓ CMM checks thisAuthor contributions via CRediT and competing-interests declarations for all authors.
Source: nature.com · verified Jun 16, 2026
Trial registration & CONSORT
✓ CMM checks thisProspective trial registration with the number reported, and CONSORT reporting for randomised trials.
Flag: a clinical trial with no registration number.
Source: consort-spirit.org · verified Jun 16, 2026
Code availability
✓ CMM checks thisA code availability statement where custom code was central to the findings.
Source: nature.com · verified Jun 16, 2026
Translational significance
Editorial, not auto-checkableWhether the findings are important for translational or clinical medicine.
Editorial judgement, not auto-checkable.
Source: nature.com · verified Jun 16, 2026
Nature Medicine follows Nature-portfolio editorial policies plus clinical-research expectations; this page is based on those policies and the journal's author instructions. CheckMyManuscript checks presence and structure, not methodological quality. Verify the live guidelines before submitting, last checked 16 June 2026.
Nature Medicine is a Nature-portfolio journal for biomedical, translational, and clinical research. It applies the shared Nature-portfolio policies, data availability, a life-sciences reporting summary, CRediT, competing interests, and code availability, alongside clinical-research expectations such as trial registration and CONSORT for trials. CheckMyManuscript screens your manuscript for the presence and structure of these elements before submission.
What CheckMyManuscript checks, and what it does not
CheckMyManuscript flags structural signals: a weak data availability statement, a missing reporting summary, absent CRediT or competing-interests declarations, or a missing trial registration number. It does not judge translational importance or methodological quality. Use the checker as a pre-submission completeness screen, not a compliance certificate.
Also see: Nature checker | Nature Communications checker | CONSORT checklist checker
What gets returned before review at Nature Medicine
Common structural reasons biomedical manuscripts are returned at the editorial screen, each maps to a signal CMM can flag.
1.
Weak data availability
No repositories or accession numbers in the data availability statement.
CMM checks for: Data availability statement
2.
Reporting summary missing
A life-sciences study without a completed reporting summary.
CMM checks for: Reporting summary
3.
Trial registration missing
A clinical trial with no registration number.
CMM checks for: Trial registration & CONSORT
4.
CRediT or competing interests absent
Author contributions or competing-interests declarations missing.
CMM checks for: CRediT & competing interests
Nature Medicine checks
Data availability
Flags a data availability statement without repositories or accession numbers.
Reporting summary
Flags a missing life-sciences reporting summary.
CRediT & competing interests
Flags missing author-contribution or competing-interests declarations.
Trial registration & CONSORT
Flags missing trial registration or CONSORT reporting for trials.
Code availability
Flags a missing code-availability statement where relevant.
Checks relevant to this topic
Part of our 80+ automated checks
Data availability
Repositories and accession numbers stated.
Reporting summary
Life-sciences reporting summary present.
CRediT & competing interests
Author contributions and competing interests stated.
Trial registration
Trial registration number present for trials.
Code availability
Code-availability statement present where relevant.
The practical edge your peers already use
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PhD Candidate, UFPE
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Félix
Postdoc Researcher, Max Planck Institute for Evolutionary Biology
A round of suggestions helped to generally refine the text of my paper and, moreover, to present some of its key points in a more focused form.
Oleg
Professor, Pirogov Russian National Research Medical University
I use it to review my students' papers. It instantly highlights typos, missing references, and unclear sections, helping me focus my feedback on the quality of the research instead of surface errors.
Ilyass
Professor in Mechanical Engineering, ÉTS Montréal
I relied on it throughout my thesis to strengthen my writing. It suggested clearer phrasing, improved flow between sections, and ensured my references were complete before the final deadline.
Manon
Master's Student in Speech Therapy
I write research in both Portuguese and English, and it adapts perfectly to either language. It provided precise feedback in Portuguese, helping me maintain academic tone and consistency across my drafts.
Afonso
PhD Candidate, UFPE
It gave excellent advice on how to rephrase and present ideas more clearly and concisely. The suggestions helped me refine my arguments and make my research more impactful.
Félix
Postdoc Researcher, Max Planck Institute for Evolutionary Biology
A round of suggestions helped to generally refine the text of my paper and, moreover, to present some of its key points in a more focused form.
Oleg
Professor, Pirogov Russian National Research Medical University
Frequently asked questions
Nature Medicine is a Nature-portfolio journal focused on biomedical, translational, and clinical research, while the Nature flagship covers breakthroughs across all sciences. Nature Medicine shares the portfolio policies (data availability, reporting summary, CRediT) and adds clinical-research expectations such as trial registration and CONSORT.
Yes. Like other Nature-portfolio journals, Nature Medicine requires a completed life-sciences reporting summary for applicable studies, submitted with the manuscript and published with accepted papers.
No. CheckMyManuscript checks the presence and structure of required elements such as data availability, the reporting summary, and trial registration. It does not judge translational importance or methodological quality, and it does not replace peer review.